Insulin resistance is a condition in which the body’s cells respond less effectively to insulin, disrupting glucose utilization and increasing the risk of chronic hyperglycemia. It is considered one of the key mechanisms in the development of prediabetes and type 2 diabetes.
It is often associated with metabolic syndrome, abdominal obesity, a sedentary lifestyle, and genetic predisposition. Treatment usually involves changes in diet and physical activity; the need for medication is determined by a doctor based on the results of an examination.