Bitter glycosides are a group of organic compounds found in various plants and have a characteristic bitter taste. They consist of a sugar molecule bound to the heap to taste by the aglycone part through a glycosidic bond. Bitter glycosides perform a protective function in plants, repelling pests and protecting plants from being eaten. In medicine and pharmacology, bitter glycosides are used for their medicinal properties, in particular to stimulate appetite and improve digestion.

Examples of bitter glycosides include amarogentin and genciopiconoside, found in gentian (Gentiana), as well as salicin, found in willow bark (Salix). Bitter glycosides stimulate the secretion of digestive juices and improve appetite, which is why they are often used as treatments for dyspepsia and other digestive disorders. In addition, some bitter glycosides have anti-inflammatory, antipyretic and analgesic properties. The use of preparations containing bitter glycosides requires compliance with dosage recommendations and consultation with a doctor, as they may have side effects and contraindications.