Introduction to Coenzyme Q10
Coenzyme q10 what is it?
Coenzyme Q10, also known as ubiquinone, is a substance present in every cell in our body. It belongs to the class of coenzymes, which means that it plays an important role in various biochemical processes, supporting their normal functioning.
Coenzyme Q10 has a vitamin-like structure and contains ten isoprenyl residues, which determines its name. It is located in the mitochondria – the energy centers of cells, where it participates in the formation of ATP (adenosine triphosphate), the main source of energy for cells.
Functions and role of coenzyme Q10 in the body
Coenzyme Q10 performs a number of important functions in the body. It plays a key role in the process of cell respiration by participating in the transfer of electrons in mitochondria. This is a process known as the respiratory chain that leads to the formation of ATP.
In addition, coenzyme Q10 is a powerful antioxidant. It protects cells from the effects of free radicals – unstable molecules that can damage cellular structures and cause oxidative stress. Thus, coenzyme Q10 contributes to the maintenance of healthy cells and organs.
The health value of coenzyme Q10
Coenzyme Q10 is not only a necessary factor for energy production in cells, but also has anti-inflammatory properties. It helps strengthen the immune system and protect the body from various diseases.
Moreover, coenzyme Q10 has a positive effect on the cardiovascular system. It is able to improve the contractility of the heart muscle, lower blood pressure and improve blood circulation. Coenzyme Q10 can also lower blood cholesterol levels and prevent oxidative stress associated with cardiovascular disease.
A review of 14 studies found that people with heart failure who took CoQ10 supplements had a lower risk of death and greater physical performance compared to those who took a placebo. It appears that taking CoQ10 may help restore optimal levels of energy production, reduce oxidative damage, and improve heart function – all of which can help treat heart failure.
Some studies also show a link between coenzyme Q10 and skin health. Ubiquinone helps protect the skin from free radical damage, helps moisturize and improves the overall structure of the skin. This makes it a popular ingredient in cosmetic products designed for skin care. When CoQ10 is applied directly to the skin, it can help reduce oxidative damage caused by UV rays and reduce the depth of wrinkles.
Coenzyme Q10 is an endogenous substance, that is, it is produced by the body on its own. However, with age, the production of this coenzyme may decrease. Therefore, some people may need to supplement with coenzyme Q10 in the form of dietary supplements.
Although coenzyme Q10 is generally well tolerated, it’s always a good idea to consult your doctor before starting supplementation, especially if you have any chronic medical conditions or are taking other medications.
Benefits of Coenzyme Q10
Supports a healthy heart and circulation
Coenzyme Q10 has a direct effect on the cardiovascular system and may play an important role in maintaining its health. This is especially useful for people with cardiovascular disease or an increased risk of developing it.
In addition, coenzyme Q10 contributes to vasodilation and lowering blood pressure. It can improve blood circulation, provide adequate oxygen and nutrients to organs and tissues, and reduce the risk of developing cardiovascular diseases such as hypertension and coronary heart disease.
Antioxidant properties of coenzyme Q10
One of the key benefits of coenzyme Q10 is its antioxidant properties. Coenzyme Q10 helps protect cells from free radicals that can damage cells’ DNA, proteins, and lipids. This is due to its ability to neutralize free radicals and prevent oxidative stress.
Oxidative stress can be associated with a variety of diseases, including cardiovascular disease, cancer, diabetes, as well as aging. Therefore, the use of coenzyme Q10 as a dietary supplement or through nutrition can help improve overall health and protect cells from damage.
Energy charge and improvement of physical endurance
Coenzyme Q10 plays an important role in the formation of ATP, the main source of energy for cells. Therefore, its presence in sufficient quantities in the body can help increase energy levels and improve physical endurance. Coenzyme Q10 promotes more efficient muscle function, improves muscle contractility and reduces fatigue.
Many studies have shown that taking coenzyme Q10 can lead to an increase in the maximum amount of oxygen that the body is able to use during physical activity. This can lead to improved aerobic endurance and increased physical performance.
In addition, coenzyme Q10 may have a positive effect on recovery after exercise and help reduce muscle inflammation. This is especially important for athletes and people engaged in intense training.
It is important to note that the effects of coenzyme Q10 on physical endurance and energy levels can vary from person to person and depend on their overall health.
Sources of coenzyme Q10
Foods rich in coenzyme Q10
Coenzyme Q10 can be obtained not only through dietary supplements, but also by eating certain foods. It is present in a variety of foods, both animal and plant-based.
Some of the animal sources of coenzyme Q10 include meat, especially liver, heart, and kidneys, fish (especially sardines and mackerel), dairy products (milk, cheeses), and eggs. Plant sources include nuts, soybean oil, spinach, broccoli, and soybeans.
However, the content of coenzyme Q10 in foods may be low, and its level may vary depending on the way food is prepared and stored. Therefore, in case of need of additional intake of coenzyme Q10, nutritional supplements are usually used.
Safety issues and contraindications
It is not recommended for children, pregnant women, lactating women and with individual sensitivity to the components of the product.
It is also worth noting that coenzyme Q10 is not a panacea and is not a substitute for a healthy lifestyle and a balanced diet. It can be a useful supplement for maintaining overall health, but its effectiveness can vary from person to person.
How to take coenzyme Q10
Coenzyme Q10 dosage recommendations
Coenzyme Q10 is available in supplement form that can be purchased at the pharmacy. It is recommended for adults to take one capsule per day with meals. The recommended course of admission is 4-6 weeks. 1 capsule contains: coenzyme Q10 – 30 mg; lactose, calcium stearate.
When and how best to take coenzyme Q10
Coenzyme Q10 can be taken at any time of the day, preferably with meals, to improve its absorption by the body. Some studies have shown that taking coenzyme Q10 along with fatty foods can increase its absorption.
It is important to remember that coenzyme Q10 is not a substitute for drugs, and it should not be used for self-medication. If you have any medical condition or need medical treatment, consult a qualified physician for advice and guidance.
Scientific research and testimonials
Current research on coenzyme Q10
There is a significant amount of scientific research on coenzyme Q10 and its role in the body. Some of them confirm its positive effects on health and well-being, especially in the areas of cardiovascular health and antioxidant protection.
Recent studies have shown that taking coenzyme Q10 may help reduce symptoms of heart failure, improve heart function, and reduce the risk of cardiovascular disease. It can also have a positive effect on blood pressure and cholesterol readings, which contributes to the maintenance of cardiovascular health.
Coenzyme Q10 is also of interest in the field of anti-aging and protecting cells from oxidative stress. Some studies have shown its potential in improving skin quality, reducing the appearance of wrinkles, and improving overall skin health.
User reviews on the use of coenzyme Q10
User reviews of the use of coenzyme Q10 often indicate its positive effects on the body. Many users note an improvement in energy levels, general well-being, increased physical endurance with regular intake of coenzyme Q10.
In addition, there are reports of improved skin condition, reduced inflammation, reduced fatigue and increased cognitive function.
Conclusion
Coenzyme Q10 plays an important role in the body by supporting energy processes, providing antioxidant protection, and promoting cardiovascular health.
Coenzyme Q10 can be obtained from certain foods, but if additional intake is needed, dietary supplements are usually used.
Overall, coenzyme Q10 represents an important factor for health and well-being. Its regular consumption can have a positive effect on the cardiovascular system, energy metabolism and skin condition.
It is important to remember that coenzyme Q10 is not a substitute for medication and should not be used for self-medication. It can be a useful addition to a healthy lifestyle, a balanced diet, and regular physical activity.
Literature:
- Lei L, Liu Y. Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials. BMC Cardiovasc Disord. 2017 Jul 24;17(1):196. doi: 10.1186/s12872-017-0628-9. PMID: 28738783; PMCID: PMC5525208.
- Wu H, Zhong Z, Lin S, Qiu C, Xie P, Lv S, Cui L, Wu T. Coenzyme Q10 Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice. Biomed Res Int. 2020 Aug 19;2020:9039843. doi: 10.1155/2020/9039843. PMID: 32923487; PMCID: PMC7453241.
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Pharmacol. 2022 Aug 24;13:883251. doi: 10.3389/fphar.2022.883251. PMID: 36091835; PMCID: PMC9449413.
- Mantle D, Dybring A. Bioavailability of Coenzyme Q10: An Overview of the Absorption Process and Subsequent Metabolism. Antioxidants (Basel). 2020 May 5;9(5):386. doi: 10.3390/antiox9050386. PMID: 32380795; PMCID: PMC7278738.
Author: Natalia Kandybey, Candidate of Pharmaceutical Sciences, Quality Director of the Pharmaceutical Factory “Viola”